COMPERISON OF “OLD” AND “NEW” ACUTE PHASE REACTANTS IN PATIENTS WITH COMMUNITY ACQUIRED PNEUMONIA AND DIABETS MELLITUS 2 TYPE AS INFLAMMATORY CHANGES MARKERS

The aim of the study was to evaluate “old” (WBC count) and “new” inflammatory biomarkers in hospitalized patients with non-severe community-acquired pneumonia with\without Diabetes Mellitus 2 type. Materials methods. At inclusion, clinical laboratory parameters were recorded CRB-65 evaluated. A total 131 adult CAP included this prospective study. Levels pro-inflammatory (IL-1β, IL-8, TNF-α), anti-inflammatory (IL-10) cytokines markers inflammation (CRP, complete blood determined at beginning disease (day O) 48-72 hours. Results. level leukocytes CBC significantly higher main group disease, as well after 10 ± days from day 0 number episodes leukocytosis > · 109 / l (8.5% vs. 2%, respectively, p <0,05). There no statistically significant difference between studied levels both groups without concomitant diabetes. a tendency cases "recovery" CRP during hospitalization ≥ 21.8 pg ml (22% 48%, <0.1). Conclusion. It can be assumed that such low dynamics is associated involutive changes immune system due older age influence DM on reactivity type response suppression also explain absence concentration compered